Acne Wash, 2 % liquid soap

Drug form: Liquid (for external use)

ATC category: Agents for acne treatment

Trade name – Acne Wash International non-property name– Salicylic acid Composition Each ml contains: active ingredient: salicylic acid- 20 mg inactive ingredients: - cocamidopropyl betaine, polyquaternium 10, sodium laureth sulfate, sodium chloride, disodium EDTA, methylparaben, aroma apple, color apple green, purified water. Chemical name and CAS number 2-hydroxybenzoic acid, [69-72-7]. Pharmacological group and ATC code Dermatological drug, ATC code D02AF. Pharmacological action Pharmacodynamic properties Human comedones, naturally or coal tar induced, are firmly anchored and are dislodged with great difficulty. Most classic "peeling" agents are ineffective: they are merely irritants which cause scaling, creating the illusion of comedolysis. While salicylic acid is an irritant its efficacy is dependent on specific pharmacological effects. It seems to detach horny cells from each other by weakening the intercellular cement. As a result, the comedones tend to undergo disorganisation. The effect is probably a good deal more complex. Salicylic acid penetrates skin readily and increases turnover which also favours exfoliation of the comedo. In concentrations of 0.5 to 2% it significantly reduces the formation of microcomedones, which are the precursors of all other acne lesions. Pharmacokinetics There is no evidence of any systemic absorption from the use of Acne Wash. Uses Acne vulgaris. Dosage and administration Acne Wash used topically by applying on wet surface of the face 2 times a day. For this, apply the required amount of liquid soap on the palms, add water and rub until foaming. Massage the face, then rinse thoroughly with water. The effect comes not earlier than after two months of usage . Adverse effects When applied topically salicylic acid solution the following local reactions are described: dry skin, itching, redness, peeling, burning sensation. Acne Wash contains methylparaben, that may cause allergic reactions (possibly delayed). Contraindications - Hypersensitivity to salicylic acid and to other ingredients. - Children's age (till 12 years). Precautions Avoid contact with the eyes and mucous membranes. In case of accidental contact, wash thoroughly with water. Do not apply it in the presence of the inflammatory focus, injuries and infections of the skin. Do not be impose hermetic bandage on the face. The simultaneous use of ACNE WASH with other topical anti-acne preparations is contraindicated, as side effects may increase . Children have likelihood of developing topical side effects higher due to high suction capacity of their skin. Do not use preparation for a long time. Pregnancy and breastfeeding If it is necessary the appointment of the preparation during pregnancy should be related to the alleged useness with the risk of possible complications. If it is necessary the appointment of the preparation during breastfeeding should solve the termination of breastfeeding. Drug interactions In a joint application of topical products (alcoholic solutions, medical cosmetics, soap and other anti-acne agents) skin dryness and irritation are observed . Expressed irritation observes in the combined use of ACNE WASH with keratolytic preparations and topical preparations containing retinol and tretinoin. Prescription status To be dispensed without prescription. Identification A greenish viscous liquid with an apple odor. Presentation 100 ml of liquid soap is filled into bottles (inside package). The bottles are packed and inserted with the leaflet into cardboard boxes (outer package). Storage conditions Store at temperature not higher than 200C, in a dry place, out of the reach of children. Protect from light. Expiry date 3 years.