Each tablet contains:

Active ingredient: Dapsone – 100 mg;

For a full list of excipients, see section List of excipients.

Posology

Adults and children over 12 years:

Multibacillary leprosy (3-drug regimen): 100mg daily for at least two years.

Paucibacillary leprosy (2-drug regimen): 100mg daily for at least six months.

Malaria prophylaxis: 100mg weekly with 12.5mg pyrimethamine.

Dermatitis herpetiformis: Initially 50mg daily, gradually increased to 300mg daily if required. Once lesions have begun to subside, the dose should be reduced to a minimum as soon as possible, usually 25-50mg daily, which may be continued for a number of years. Maintenance dosage can often be reduced in patients receiving a gluten-free diet.

Pneumocystis carinii pneumonia: In combination with trimethoprim, 50-100mg daily; 100mg twice weekly or 200mg once weekly.

Children 6-12 years:

Multibacillary leprosy (3-drug regimen): 50mg daily for at least two years.

Paucibacillary leprosy (2-drug regimen): 50mg daily for at least six months.

Elderly: Dosage should be reduced in the elderly where there is an impairment of hepatic function.

Method of Administration

For oral administration.

ATC code/pharmacological group: J04BA02

Dapsone is a sulfone active against a wide range of bacteria.

List of excipients

Microcrystalline cellulose,

maize starch,

magnesium stearate,

aerosil 200.

For more detailed information about the drug, click: http://pharm.cals.am/pharm/data/drug_134425/1736329537406.pdf