Each Lorazepam 1 mg tablet contains:

active ingredient: lorazepam – 1 mg

For a full list of excipients, see section List of excipients.

Route of administration: oral

Treatment to be given:

• Under close medical supervision
• At the lowest effective dose
• For the shortest possible duration (not exceeding 4 weeks)

Doses should be individualized

Extension of use should not take place without further clinical evaluation

Chronic use not recommended (little is known of the long-term safety and efficacy; potential for dependence–see section Special warnings and precautions for use).

When treatment is started the patient should be informed that

• treatment will be of limited duration
• the dosage will be progressively decreased
• there is a possibility of rebound phenomena

Dosage:

Adults:

Anxiety: 1-4mg daily in divided doses. Insomnia: 1-2mg before retiring

Premedication before operative dentistry or general surgery:

2-3mg the night before operation 2-4mg one to two hours before the procedure

Elderly and debilitated patients:

For elderly and debilitated patients reduce the initial dose by approximately 50% and adjust the dosage as needed and tolerated (see section Special warnings and precautions for use).

Children (aged 5-13 years):

Premedication: 0.5-2.5mg at 0.05mg/kg to the nearest 0.5mg according to weight, not less than one hour before operation.

Patients with Renal or Hepatic impairment:

Lower doses may be sufficient in these patients (See section Special warnings and precautions for use). Use in patients with severe hepatic insufficiency is contraindicated. (See section Fertility, pregnancy and lactation).

Pharmacotherapeutic group: Anxiolytics. Benzodiazepine derivatives.

ATC code: NO5BA06

List of excipients

Lorazepam 1 mg and 2 mg tablets

microcrystalline cellulose

lactose monohydrate

maize (corn) starch

povidone

sodium starch glycolate

magnesium stearate

talc purified.

For more detailed information about the drug, click: http://pharm.cals.am/pharm/data/drug_134425/1736329537406.pdf