Each coated tablet contains 25 mg levomepromazine maleate

For excipients, see 6.1.

Dosage varies with the condition under treatment and the individual response of the patient.

1. Terminal illness

Levomepromazine coated tablets 25mg may be substituted for the injection if oral therapy is more convenient, the dosage being 12.5mg to 50mg every 4 to 8 hours.

Elderly

No specific dosage recommendations.

2. Psychiatric conditions

Adults

Ambulant patients: initially the total daily oral dose should not exceed 25mg to 50mg usually divided into 3 doses; a larger portion of the dosage may be taken at bedtime to minimise diurnal sedation. The dosage is then gradually increased to the most effective level compatible with sedation and other side effects.

Bed patients: initially the total daily oral dosage may be 100mg to 200mg, usually divided into 3 doses, gradually increased to 1g daily if necessary. When the patient is stable attempts should be made to reduce the dosage to an adequate maintenance level.

Children

Children are very susceptible to the hypotensive and soporific effects of levomepromazine. It is advised that a total daily oral dosage of 1½ tablets should not be exceeded. The average effective daily intake for a ten year old is ½ to 1 tablet.

Elderly patients

It is not advised to give levomepromazine to ambulant patients over 50 years of age unless the risk of a hypotensive reaction has been assessed.

ATC Code: NO5AA02

Pharmacotherapeutic group: Antipsychotics.

List of excipients

Tablet core:

Microcrystalline cellulose

Lactose monohydrate

Povidone K30

Maize starch

Magnesium stearate

Sodium starch glycolate

Coating:

Titanium dioxide

Hypromellose

Talc purified

Propylene glycol.

For more detailed information about the drug, click: http://pharm.cals.am/pharm/data/drug_134425/1736329537406.pdf