Each gram contains:

active ingredient: permethrin – 50 mg;

For a full list of excipients, see section List of excipients

Treatment of scabies

Adults and adolescents over 12 years of age:

Apply up to 30 g of cream (corresponding to 60% tube of 50 g).

Paediatric population

Children aged from 6 – 12 years:

Apply up to 15 g of cream (corresponding to 30% tube of 50 g).

Children aged from 2 months – 5 years:

Up to 7.5 g of cream (corresponding to 15% tube of 50 g).

The safety and efficacy of Permethrin cream in children under 2 months of age have not been established. No data are available.

Treatment of crab lice

Adults over 18 years of age:

Apply up to 30 g of cream (corresponding to 60% tube of 50 g).

Method of administration

For cutaneous use only. The medicinal product must not be swallowed.

Carefully apply a thin layer of cream to the skin (cutaneous use).

For treatment of scabies:

Adults should apply the cream uniformly to the whole body including the neck, palms of the hands and soles of the feet. The head and face can be spared unless scabies efflorescences are present in this region.

On application, the areas between the fingers and toes (also under the finger- and toe-nails), the wrists, elbows, armpits, external genitalia and the buttocks should be especially carefully treated.

Paediatric population

Children should apply the cream uniformly to the whole body, including the palms of the hands, soles of the feet, neck, face, ears, and scalp. Parts of the skin around the mouth (because the cream could be licked off) and the eyes should be spared. Children should be kept from licking the cream from the hands. If necessary, children should wear gloves.

Only limited experience is available with Permethrin cream in children aged 2 months to 23 months. Therefore treatment must be given only under close medical supervision in this age group.

Elderly:

Elderly patients (over 65 years) should use the cream in the same way as adults, but in addition, the face, ears and scalp should also be treated. Care should be taken to avoid applying the cream to areas of skin around the eyes.

Permethrin cream should be applied to clean, dry, cool skin. If the patient has taken a warm bath prior to treatment the skin should be allowed to cool before the cream is applied.

Permethrin cream is a vanishing cream and when rubbed gently into the skin it will disappear. Therefore, there is no need to continue to apply cream to the skin until it remains detectable on the surface.

Older children should be supervised by an adult when applying to ensure that a thorough treatment is administered.

The whole body should be washed thoroughly 8 – 12 hours after treatment.

Approximately 90% of individuals are cured with a single application of cream. If necessary, a second application may be given not less than 7 days after the initial application, if there are no signs of the original lesions healing or if new lesions are present.

For treatment of crab lice in adults:

Sufficient cream should be applied to cover the pubic region, peri-anal (around the anus), inner thighs down to the knees and any hair that grows up from the pubic area to the chest/stomach.

For treatment of crab lice in adults, the cream should be left on the skin for 24 hours, after which the treatment areas should be washed thoroughly.

Any facial hair (beards, moustaches) and eyelashes should be checked for the presence of live lice and eggs. Cream should be applied to any facial hair, carefully avoiding eyes. If live lice or eggs are found on the eyelashes they should be removed carefully using tweezers. Cream should not be applied to the eyelashes because the cream can cause moderate eye irritation.

Pharmacotherapeutic group: Еctoparasiticides, incl. Scabicides. Pyrethrines, incl. synthetic compounds. Permethrin, combinations.

ATC code – P03AC04.

List of excipients

Ceteareth-12,

Ceteareth-20,

Cetostearyl alcohol,

Liquid paraffin,

Propylene glycol,

Dimethicone,

Methylparaben,

Propylparaben,

Glycerol monostearate,

Water purified.

For more detailed information about the drug, click: http://pharm.cals.am/pharm/data/drug_134482/1734095746965.pdf